Insulin sensitivity and vascular disease in maturity-onset diabetics
- 15 November 1969
- Vol. 4 (5680), 397-399
- https://doi.org/10.1136/bmj.4.5680.397
Abstract
In 27 maturity-onset diabetics of more than 10 years' duration there was a significant tendency for both atherosclerosis and microangiopathy to be associated with a reduction in the acute hypoglycaemic effect of intravenous beef insulin. This finding is identical to that in a group of 51 insulin-dependent diabetics previously reported. It is suggested that insulin insensitivity probably precedes the appearance of vascular disease in diabetes and may be implicated in its production.Keywords
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