Bovine rotavirus with rearranged genome reassorts with human rotavirus

Abstract
Bovine rotavirus (brv) possessing a rearranged genome [Hundley et al. (1985), Virology 143: 88–103] was found to reassort with tissue culture-adapted group A human rotavirus carrying a standard genome. The rearranged part of the brv genome containing segment 5-specific sequences was exchanged with the normal RNA segment 5 of the human rotavirus in some of the reassortants.