Stable absolute flow estimation with Doppler OCT based on virtual circumpapillary scans
Open Access
- 1 October 2010
- journal article
- research article
- Published by Optica Publishing Group in Biomedical Optics Express
- Vol. 1 (4), 1047-1059
- https://doi.org/10.1364/BOE.1.001047
Abstract
Doppler optical coherence tomography has the capability to measure blood flow quantitatively and in vivo. As only the axial component of the velocity can be assessed, the measurements have to be corrected for the angle of the vessels. We present a novel approach to extract quantitative flow data from circumpapillary scans in vivo on the human retina by registering the circular scan to a reference volume scan and extracting the angle directly from the volume. In addition, we perform phase unwrapping and interpolation of the flow under the assumption of a parabolic flow profile. We demonstrate the repeatability of the methods by applying it to different retinal vessels, achieving coefficients of variation of the average velocity of 3 to 8%. Results on the pulsatility and resistance index are also presented.This publication has 35 references indexed in Scilit:
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