Effects of tryptophan depletion vs catecholamine depletion in patients with seasonal affective disorder in remission with light therapy.
Open Access
- 1 June 1998
- journal article
- clinical trial
- Published by American Medical Association (AMA) in Archives of General Psychiatry
- Vol. 55 (6), 524-530
- https://doi.org/10.1001/archpsyc.55.6.524
Abstract
SEASONAL AFFECTIVE disorder, winter type (SAD), is a condition characterized by regularly occurring depressions in fall and winter, alternating with nondepressed periods in spring and summer.1 Light therapy with bright, fluorescent white light has been shown to be an effective antidepressant.1-3 Evidence suggests that brain monoaminergic systems may be involved in the pathogenesis of SAD and in the mechanism of action of light therapy.Keywords
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