An Adenylic Acid-Rich Sequence in Messenger RNA of HeLa Cells and Its Possible Relationship to Reiterated Sites in DNA
- 1 June 1971
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 68 (6), 1321-1325
- https://doi.org/10.1073/pnas.68.6.1321
Abstract
Messenger RNA from HeLa cells contains, as part of the polynucleotide chain, RNase-resistant sequences that are labeled by adenosine but not by uridine. Heterogeneous nuclear RNA also contains adenylate-rich RNase-resistant regions, but in lower proportion than messenger RNA. Hybridization to DNA of 32P-labeled messenger RNA reveals that some of the adenylate-rich region is included in the rapidly-hybridizing fraction.Keywords
This publication has 25 references indexed in Scilit:
- Fractionation of heterogeneous nuclear RNA: Rates of hybridization and chrosomal distribution of reiterated sequencesJournal of Molecular Biology, 1970
- SV40-Specific RNA in the Nucleus and Polyribosomes of Transformed CellsProceedings of the National Academy of Sciences of the United States of America, 1970
- Gene Regulation for Higher Cells: A TheoryScience, 1969
- The Isolation and Characterization of Adenosine Monophosphate-rich Polynucleotides Synthesized by Ehrlich Ascites CellsJournal of Biological Chemistry, 1969
- Messenger RNA-protein complexes and newly synthesized ribosomal subunits: Analysis of free particles and components of polyribosomesJournal of Molecular Biology, 1968
- Related base sequences in the DNA of simple and complex organisms. I. DNA/DNA duplex formation and the incidence of partially related base sequences in DNABiochemical Genetics, 1968
- In vivo labeling patterns of free polyribosomes: Relationship to tape theory of messenger ribonucleic acid functionJournal of Molecular Biology, 1967
- High molecular weight nonribosomal-type nuclear RNA and cytoplasmic messenger RNA in HeLa cells.Proceedings of the National Academy of Sciences of the United States of America, 1966
- An improved procedure for measuring the distribution of P32O4− among the nucleotides of ribonucleic acidAnalytical Biochemistry, 1964
- DEMONSTRATION OF AN UNSTABLE RNA AND OF A PRECURSOR TO RIBOSOMAL RNA IN HELA CELLSProceedings of the National Academy of Sciences, 1963