Regulation of wingless transcription in the Drososphila embryo
Open Access
- 1 January 1993
- journal article
- Published by The Company of Biologists in Development
- Vol. 117 (1), 283-291
- https://doi.org/10.1242/dev.117.1.283
Abstract
The segment polarity gene wingless (wg) is expressed in a complex pattern during embryogenesis suggesting that it plays multiple roles in the development of the embryo. The best characterized of these is its role in cell pattening in each parasegment, a process that requires the activity of other segment polarity genes including patched (ptc) and hedgehog (hh). Here we present further evidence that ptc and hh encode components of a signal transduction pathway that regulate the expression of wg transcription following its activation by pair-rule genes. We also show that most other aspects of wg expression are independent of this regulatory network.Keywords
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