Primary Pulmonary Hypertension
Open Access
- 1 December 1962
- journal article
- research article
- Published by Ovid Technologies (Wolters Kluwer Health) in Circulation
- Vol. 26 (6), 1358-1369
- https://doi.org/10.1161/01.cir.26.6.1358
Abstract
The clinical features of 16 patients with primary pulmonary hypertension are reviewed. Repeated cardiac catheterizations at intervals of 1 to 4 years during the course of the disease were performed in five patients. In three of the five patients there was a progressive increase in pulmonary artery pressure, total pulmonary resistance, and a decline in cardiac output. In two patients the pulmonary hemodynamics remained unchanged between studies at intervals of 2 and 4 years. Arterial oxygen saturation decreased with progression of the disease, presumably reflecting the appearance of an uneven distribution of pulmonary capillary flow. The course of the illness was variable and unaffected by any mode of therapy, including long-term anticoagulation.Keywords
This publication has 3 references indexed in Scilit:
- PRIMARY PULMONARY HYPERTENSION: REPORT OF SIX CASES AND REVIEW OF LITERATUREAnnals of Internal Medicine, 1958
- TWO CASES OF PRIMARY PULMONARY HYPERTENSION WITH SUDDEN DEATH ASSOCIATED WITH THE ADMINISTRATION OF BARBITURATESAnnals of Internal Medicine, 1955