Cardiovascular Changes during Deep Halothane Anaesthesia in Infants and Children
Open Access
- 1 August 1988
- journal article
- research article
- Published by SAGE Publications in Anaesthesia and Intensive Care
- Vol. 16 (3), 285-291
- https://doi.org/10.1177/0310057x8801600308
Abstract
Cardiac output, blood pressure and heart rate were measured with noninvasive techniques before, during and after induction of anaesthesia with halothane and after intubation in unpremedicated infants and in diazepam-atropine premedicated children presenting for elective surgery. Cardiac output was measured with pulsed doppler echocardiography. Left ventricular shortening fraction was estimated with M-mode echocardiography during induction. Induction with halothane in infants caused significant decrements in blood pressure, cardiac index, stroke volume index and significant depression of left ventricular shortening fraction. Induction with halothane in diazepam-atropine premedicated children caused a significant increase in heart rate but significant decreases in blood pressure, stroke volume index and left ventricular shortening fraction while cardiac index decreased slightly. Intubation in infants caused a mild increase in heart rate compared with pre-induction values but blood pressure, cardiac index and stroke volume index remained below pre-induction values. Intubation in diazepam-atropine premedicated children caused significant increases in heart rate and cardiac index, and a nonsignificant increase in blood pressure but stroke volume index remained significantly below pre-induction values. Healthy infants and children tolerate induction of anaesthesia with halothane to a depth to permit intubation but large reductions in cardiac output and myocardial contractility are expected with subsequent reductions in blood pressure.Keywords
This publication has 22 references indexed in Scilit:
- Pulsed Doppler and Two-dimensional EchocardiographyAnesthesiology, 1987
- COMPARISON OF ENFLURANE, HALOTHANE, AND ISOFLURANE FOR OUTPATIENT PEDIATRIC ANESTHESIAAnesthesiology, 1984
- Noninvasive Doppler determination of cardiac output in man. Clinical validation.Cell Metabolism, 1983
- Noninvasive pulsed Doppler determination of cardiac output in neonates and childrenThe Journal of Pediatrics, 1982
- Cardiovascular Depression during Halothane Anesthesia in InfantsAnesthesia & Analgesia, 1982
- Recommendations regarding quantitation in M-mode echocardiography: results of a survey of echocardiographic measurements.Cell Metabolism, 1978
- Echocardiography — Application in Assessing Cardiac Performance in Clinical CareAnesthesiology, 1978
- The Cardiovascular Effects of Halothane in Man during Spontaneous VentilationAnesthesiology, 1972
- THE EFFECTS OF HALOTHANE ON MYOCARDIAL CONTRACTILE FORCE AND VASCULAR RESISTANCEAnesthesiology, 1961
- THE EFFECT OF FLUOTHANE?? on myocardial contractile force in manAnesthesia & Analgesia, 1961