Investigations on the mechanism of stimulation of non-specific immunity by bacterial lipopolysaccharides.

Abstract

The stimulation of non-specific immunity by lipopolysaccharides could not be correlated with the serum properdin level at the time of challenge. Zymosan was effective in stimulating an increase in properdin without raising resistance to infection. The development of a low properdin level during Esch. coli infection did not inevitably lead to death.