Chronic radiation myelitis.

Abstract
From March 1971 to Sept. 1973, 200 patients with primary bronchogenic carcinoma received 4000 rad (40 Gy [gray]) by means of split-course accelerated fractionation. Forty-five patients (22.5%) survived more than 11 mo.; of these, 6 (13.3%) had progressive myelitis. Rapid fractionation apparently is preferred in some centers and may be undergoing a resurgence. Experience with this technique and the current understanding of the factors which affect the development of radiation myelitis are reviewed.