Iodide Transport: Inhibition by Agents Reacting at the Membrane
- 20 January 1967
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 155 (3760), 335-336
- https://doi.org/10.1126/science.155.3760.335
Abstract
Accumulation of iodide by thyroid tissue is inhibited by two phospholipase A-free proteins from cobra venom, filipin, crude phospholipase C, and lysolecithin. The venom proteins decrease K+ in tissue but do not significantly affect incorporation of phosphorus-32 into phospholipid or stimulation of this process by thyrotropin. However, filipin and crude phospholipase C, like thyrotropin, do increase phospholipid formation.This publication has 5 references indexed in Scilit:
- Metabolism of Isolated Fat CellsJournal of Biological Chemistry, 1966
- METABOLISM OF ISOLATED FAT CELLS .2. SIMILAR EFFECTS OF PHOSPHOLIPASE C (CLOSTRIDIUM PERFRINGENS ALPHA TOXIN) AND OF INSULIN ON GLUCOSE AND AMINO ACID METABOLISM1966
- Thyroidal iodide transport VI. On a possible role for iodide-binding phospholipidsBiochimica et Biophysica Acta (BBA) - Biophysics including Photosynthesis, 1964
- Thyroidal iodide transportBiochimica et Biophysica Acta, 1963
- An iodide-complexing phospholipidArchives of Biochemistry and Biophysics, 1962