The gene coding for the human T-lymphocyte CD2 antigen is located on chromosome 1p
- 1 June 1987
- journal article
- research article
- Published by Springer Science and Business Media LLC in Human Genetics
- Vol. 76 (2), 191-195
- https://doi.org/10.1007/bf00284920
Abstract
A cDNA clone encoding the human T lymphocyte sheep erythrocyte receptor [the CD2 (T11) antigen] was used as a probe to define the chromosomal location of the gene. The signal, revealed by hybridisation to Southern blots of genomic DNA from somatic cell hybrids, showed a high degree of concordance for human chromosome 1. In particular, the hybrid F4Sc13C19 which contained the short arm only of human chromosome 1 was positive. The location of the CD2 gene to 1p13 was confirmed by in situ hybridisation.This publication has 25 references indexed in Scilit:
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