The Biochemistry of the Polyamines: Spermidine and Spermine

Abstract
This review includes the following topics: assay techniques; distribution and concentration; chemical synthesis of sperm-idine and spermine; biosynthesis of spermidine and spermine; other enzymatic pathways involving sperdimine and spermine; microbiological requirements for polyamines as growth factors; stabilizing effects of polyamines; binding of polyamines to nucleic acids, lipids and heparin; pharmacology and pathology.

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