Catalysis of Ugi Four Component Coupling Reactions by Rare Earth Metal Triflates
- 21 June 2008
- journal article
- Published by American Chemical Society (ACS) in The Journal of Organic Chemistry
- Vol. 73 (14), 5595-5597
- https://doi.org/10.1021/jo800745a
Abstract
Substoichiometric quantities of scandium and ytterbium triflate increase the yield of Ugi four component coupling reactions of aromatic aldehydes 2- to 7-fold. These rare earth metal triflates enhance the reaction yields primarily via activation of the imine intermediate of this multicomponent reaction.Keywords
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