3′-Azidothymidine (Zidovudine) Inhibits Glycosylation and Dramatically Alters Glycosphingolipid Synthesis in Whole Cells at Clinically Relevant Concentrations
Open Access
- 1 September 1995
- journal article
- research article
- Published by Elsevier BV
- Vol. 270 (39), 22836-22841
- https://doi.org/10.1074/jbc.270.39.22836
Abstract
No abstract availableKeywords
This publication has 20 references indexed in Scilit:
- Mice lacking N-acetylglucosaminyltransferase I activity die at mid-gestation, revealing an essential role for complex or hybrid N-linked carbohydrates.Proceedings of the National Academy of Sciences, 1994
- THE BIOCHEMISTRY OF AIDSAnnual Review of Biochemistry, 1991
- Nuclear DNA synthesis in vitro is mediated via stable replication forks assembled in a temporally specific fashion in vivo.Molecular and Cellular Biology, 1988
- The in vitro and in vivo anti-retrovirus activity, and intracellular metabolism of 3′-azido-2′,3′-dideoxythymidine and 2′,3′-dideoxycytidine are highly dependent on the cell speciesBiochemical Pharmacology, 1988
- INHIBITORS OF THE BIOSYNTHESIS AND PROCESSING OF N-LINKED OLIGOSACCHARIDE CHAINSAnnual Review of Biochemistry, 1987
- Two procedures to remove polar contaminants from a crude brain lipid extract by using prepacked reversed‐phase columnsLipids, 1987
- Phosphorylation of 3'-azido-3'-deoxythymidine and selective interaction of the 5'-triphosphate with human immunodeficiency virus reverse transcriptase.Proceedings of the National Academy of Sciences, 1986
- Biosynthesis of glycosphingolipids by human myeloid leukemia cellsBiochemistry, 1985
- Glycosphingolipids in Cellular Interaction, Differentiation, and OncogenesisAnnual Review of Biochemistry, 1981
- [17] Labeling complex carbohydrates of animal cells with monosaccharidesMethods in enzymology, 1978