Mechanism of Hyperventilation in Acute Cerebrovascular Accidents
- 3 July 1971
- Vol. 3 (5765), 9-12
- https://doi.org/10.1136/bmj.3.5765.9
Abstract
Lumbar cerebrospinal fluid and arterial blood acid-base state were assessed in 19 patients within 24 hours of an acute cerebrovascular accident. Those with haemorrhage into the C.S.F. showed a lower C.S.F. pH and higher C.S.F. lactate than those without haemorrhage but the Pco2, was similar in the two groups, suggesting that this greater C.S.F. acidity was not responsible for a greater degree of hyperventilation. In those without haemorrhage an inverse relation was found between C.S.F. pH and arterial Pco2, suggesting that a non-chemical ventilatory drive—for example, due to central neurological damage—was responsible for the acid-base changes observed.Keywords
This publication has 11 references indexed in Scilit:
- Prognosis in Acute Cerebrovascular Accidents in Relation to Respiratory Pattern and Blood--gas TensionsBMJ, 1971
- The Effect of Dichlorphenamide on Blood and Cerebrospinal Fluid Acid-Base State in Chronic Ventilatory FailureClinical Science, 1970
- Brain Metabolism during Fasting*JCI Insight, 1967
- HYPERVENTILATION ASSOCIATED WITH LOW pH OF CEREBROSPINAL FLUID AFTER INTRACRANIAL HÆMORRHAGEThe Lancet, 1966
- Lactate and Pyruvate in the Brain of Rats During HyperventilationArchives Internationales de Physiologie et de Biochimie, 1966
- Rate of change of carbon dioxide tension in arterial blood, jugular venous blood and cisternal cerebrospinal fluid on carbon dioxide administration.The Journal of Physiology, 1965
- Central Neurogenic Hyperventilation in ManArchives of Neurology & Psychiatry, 1959
- [On the metabolite content and the metabolite concentration in the liver of the rat].1959
- The effects of want of exygen on respirationThe Journal of Physiology, 1908