Compilation and analysis of DNA sequences associated with apparent streptomycete promoters
- 1 January 1992
- journal article
- research article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 20 (5), 961-974
- https://doi.org/10.1093/nar/20.5.961
Abstract
The DNA sequences associated with 139 apparent streptomycete transcriptional start sites are compiled and compared. Of these, 29 promoters appeared to belong to a group which are similar to those recognized by eubacterial RNA polymerases containing sigma 70-like subunits. The other 110 putative promoter regions contain a wide diversity of sequences; several of these promoters have obvious sequence similarities in the -10 and/or -35 regions. The apparent Shine-Dalgarno regions of 44 streptomycete genes are also examined and compared. These were found to have a wide range of degree of complementarity to the 3' end of streptomycete 16S rRNA. Eleven streptomycete genes are described and compared in which transcription and translation are proposed to be initiated from the same or nearby nucleotide. An updated consensus sequence for the E sigma 70-like promoters is proposed and a potential group of promoter sequences containing guanine-rich -35 regions also is identified.Keywords
This publication has 97 references indexed in Scilit:
- Analysis of the promoter region of saf, a Streptomyces griseus gene that increases production of extracellular enzymesGene, 1991
- Characterization of an oxytetracycline‐resistance gene, otrA, of Streptomyces rimosusMolecular Microbiology, 1991
- Three in-frame N-terminally different proteins are produced from the repressor locus of the Streptomyces bacteriophage ?C31Molecular Microbiology, 1991
- Specific sequences downstream from −6 are not essential for proper and efficient in Vitro utilization of the Escherichia coli lactose promoterJournal of Molecular Biology, 1990
- Primary structure of AfsR, a global regulatory protein for secondary metabolite formation in Streptomyces coelicolor A3(2)Gene, 1990
- Extracellular metalloprotease gene of Streptomyces cacaoi: structure, nucleotide sequence and characterization of the cloned gene productGene, 1990
- Analysis of transcriptional control regions in the Streptomyces subtilisin-inhibitor-encoding geneGene, 1989
- The developmental fate of S. coelicolor hyphae depends upon a gene product homologous with the motility σ factor of B. subtilisCell, 1989
- Unusual transcriptional and translational features of the aminoglycoside phosphotransferase gene (aph) from Streptomyces fradiae.Genes & Development, 1989
- Structure and regulation of controlling sequences for the Streptomyces coelicolor glycerol operonJournal of Molecular Biology, 1988