Passive Cutaneous Anaphylaxis with Antigen-Antibody Complexes and Additional Antigen.

Abstract

The ability of antibody in washed specific precipitate to sensitize tissues to a subsequent injection of antigen is demonstrated. Mixtures of antigen with antibody ranging from great antigen excess to antibody excess were also effective. The amounts of combined antibody which sensitize approximate the minimum amounts of uncombined antibody required for sensitization. The continued potential for combined antibody to react in vivo with additional antigen is thus demonstrated.