A SIMPLE METHOD FOR THE ESTIMATION OF TOTAL PROTEIN CONTENT OF PLASMA AND SERUM. II. THE ESTIMATION OF TOTAL PROTEIN CONTENT OF HUMAN PLASMA AND SERUM BY THE USE OF THE FALLING DROP METHOD

Abstract

229 specimens of human plasma and serum were analyzed for total protein by the macro Kjeldahl method and refractive index and for specific gravity by the falling drop method described in part I. Linear relationships exist between the sp. gr. and the total protein content of serum and plasma as detd. by the macro Kjeldahl method. The protein content of normal and pathological sera can be estimated from the sp. gr. so detd. with a max. deviation of +0.48 gm. % and a mean deviation of [plus or minus]0.16 gm. %. This accuracy exceeds clinical requirements and is about twice as good as the refractometric method.