Chromatin: constructing the big picture
Open Access
- 28 April 2011
- journal article
- review article
- Published by Springer Science and Business Media LLC in The EMBO Journal
- Vol. 30 (10), 1885-1895
- https://doi.org/10.1038/emboj.2011.135
Abstract
Chromatin is the ensemble of genomic DNA and a large number of proteins. Various genome‐wide mapping techniques have begun to reveal that, despite the tremendous complexity, chromatin organization is governed by simple principles. This review discusses the principles that drive the spatial architecture of chromatin, as well as genome‐wide‐binding patterns of chromatin proteins.Keywords
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