Clindamycin Therapy of Cerebral Toxoplasmosis in an AIDS Patient
- 1 January 1988
- journal article
- case report
- Published by Informa UK Limited in Scandinavian Journal of Infectious Diseases
- Vol. 20 (5), 561-563
- https://doi.org/10.3109/00365548809032507
Abstract
A 47-year-old patient with AIDS and cerebral toxoplasmosis was treated with sulfadiazine pyrimethamine for 5 days. After developing a severe rash his regimen was changed to clindamycin 600 mg q 6 h intravenously and pyrimethamine 25 mg daily, given for 37 days. This resulted in improvement of clinical symptoms and complete resolution of CT scan abnormalities. Clindamycin combined with pyrimethamine may be a useful alternative therapy for cerebral toxoplasmosis in patients who can not tolerate sulfonamides.Keywords
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