The role of stress in addiction relapse
- 3 October 2007
- journal article
- review article
- Published by Springer Science and Business Media LLC in Current Psychiatry Reports
- Vol. 9 (5), 388-395
- https://doi.org/10.1007/s11920-007-0050-6
Abstract
Stress is an important factor known to increase alcohol and drug relapse risk. This paper examines the stress-related processes that influence addiction relapse. First, individual patient vignettes of stress-and cue-related situations that increase drug seeking and relapse susceptibility are presented. Next, empirical findings from human laboratory and brain-imaging studies that are consistent with clinical observations and support the specific role of stress processes in the drug-craving state are reviewed. Recent findings on differences in stress responsivity in addicted versus matched community social drinkers are reviewed to demonstrate alterations in stress pathways that could explain the significant contribution of stress-related mechanisms on craving and relapse susceptibility. Finally, significant implications of these findings for clinical practice are discussed, with a specific focus on the development of novel interventions that target stress processes and drug craving to improve addiction relapse outcomes.Keywords
This publication has 96 references indexed in Scilit:
- Enhanced Sensitivity to Stress and Drug/Alcohol Craving in Abstinent Cocaine-Dependent Individuals Compared to Social DrinkersNeuropsychopharmacology, 2007
- Enhanced Emotional and Physiological Sensitivity to Stress and Drug/Alcohol Craving in Abstinent Cocaine-Dependent Individuals Compared to Socially Drinking ControlsNeuropsychopharmacology, 2007
- Stress and drug-cue-induced craving in opioid-dependent individuals in naltrexone treatment.Experimental and Clinical Psychopharmacology, 2007
- Childhood maltreatment, perceived stress, and stress-related coping in recently abstinent cocaine dependent adults.Psychology of Addictive Behaviors, 2007
- Heart Rate Variability and Sympathetic Skin Response in Male Patients Suffering From Acute Alcohol Withdrawal SyndromeAlcohol: Clinical and Experimental Research, 2006
- The cannabis withdrawal syndromeCurrent Opinion in Psychiatry, 2006
- The Neural Correlates of Cue-Induced Craving in Cocaine-Dependent WomenAmerican Journal of Psychiatry, 2004
- Tobacco withdrawal in self-quitters.Journal of Consulting and Clinical Psychology, 1992
- Abnormal Adrenal Gland Metabolism in Opioid Addicts: Implications for Clinical TreatmentJournal of Psychoactive Drugs, 1991
- Cue Reactivity in Addictive Behaviors: Theoretical and Treatment ImplicationsInternational Journal of the Addictions, 1991