Hormone Receptors 5. Binding of Glucagon and Insulin to Human Circulating Mononuclear Cells in Diabetes Mellitus
- 1 January 1975
- journal article
- Published by Informa UK Limited in Endocrine Research Communications
- Vol. 2 (4-5), 367-376
- https://doi.org/10.1080/07435807509089009
Abstract
Preparations of human peripheral mononuclear leukocytes, containing over 85% lymphocytes, specifically bound glucagon and insulin. Binding of physiological concentrations of both hormones was seen to be substantially diminished when cells were derived from either adult-type diabetics or individuals with a unilateral genetic history of diabetes.Keywords
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