Generation of Singlet Oxygen via the Composites of Water-Soluble Thiol-Capped CdTe Quantum DotsSulfonated Aluminum Phthalocyanines
- 26 March 2008
- journal article
- letter
- Published by American Chemical Society (ACS) in The Journal of Physical Chemistry B
- Vol. 112 (15), 4465-4469
- https://doi.org/10.1021/jp711537j
Abstract
Singlet oxygen (1O2), one of the reactive oxygen species, plays an important role in many biomedical applications. The various compounds including the phthalocyanines, quantum dots (QDs) and QD complex, which may have potential to produce 1O2, thus received more and more attentions in recent years. By means of the direct detection of near-infrared 1270 nm, we found that the water-soluble thiol-capped CdTe QDs can photoproduce 1O2 in deuterated water with a low quantum yield (QY) of 1%. When sulfonated aluminum phthalocyanines (AlSPc's) were connected to these QDs, forming water-soluble QD−Pc composites, the 1O2 QY of the composites increased to 15% under the excitation of 532 nm, while little 1O2 production can be found for AlSPc alone at the same excitation because of the poor absorption of AlSPc in this region. The results of indirect measurements of 1O2, obtained from the photodegradation of the 1O2 chemical trap anthracene-9,10-diyl-bis-methylmalonate (ADMA), confirmed 1O2 yields in both QD and QD−Pc composite solutions. The QD−Pc composites have the advantage of extending the excitation region to 400−600 nm with remarkably enhanced extinction coefficients as compared with that of AlSPc. Therefore QD−Pc composites can fully utilize visible region light excitation to effectively produce 1O2, which may facilitate the applications of QD−Pc composites in broad areas.Keywords
This publication has 19 references indexed in Scilit:
- Aqueous Synthesis of Thiol-Capped CdTe Nanocrystals: State-of-the-ArtThe Journal of Physical Chemistry C, 2007
- Comparative photocatalytic efficiency of oxotitanium(IV) phthalocyanines for the oxidation of 1-hexeneJournal of Molecular Catalysis A: Chemical, 2007
- In vivooptical imaging using quantum dots for the management of brain tumorsExpert Review of Molecular Diagnostics, 2006
- Noninvasive Imaging of Quantum Dots in MiceBioconjugate Chemistry, 2003
- Hydrothermal Synthesis for High‐Quality CdTe NanocrystalsAdvanced Materials, 2003
- Quantum Dots Get WetScience, 2003
- Photodynamic TherapyJNCI Journal of the National Cancer Institute, 1998
- Photoinactivation of bacteria. Use of a cationic water-soluble zinc phthalocyanine to photoinactivate both Gram-negative and Gram-positive bacteriaJournal of Photochemistry and Photobiology B: Biology, 1996
- Photosensitizers of the porphyrin and phthalocyanine series for photodynamic therapyChemical Society Reviews, 1995
- Complexes Derived from Strong Field Ligands. XIX. Magnetic Properties of Transition Metal Derivatives of 4,4',4",4'''-TetrasulfophthalocyanineInorganic Chemistry, 1965