Alveolar Macrophages: Reduced Number in Rats after Prolonged Inhalation of Lead Sesquioxide
- 13 December 1968
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 162 (3859), 1297-1299
- https://doi.org/10.1126/science.162.3859.1297
Abstract
A decreased number of alveolar macrophages was found in washings from lungs of rats inhaling small particles of lead sesquioxide for 3 to 12 months, as compared with control animals exposed to filtered air. This result contrasts with that reported by others for animals given massive exposures to various dusts for short periods of time. Because the concentrations of lead were comparable to those observed in some industrial(150 µg/m3) or urban (10 µg/m3) environmental conditions, the results may be significant in terms of human lung clearance processes after such exposures.Keywords
This publication has 2 references indexed in Scilit:
- The Relation of Age to the Numbers of Lung Free Cells, Lung Weight, and Body Weight in RatsJournal of Gerontology, 1968
- The Fate of Inhaled Particles in the Early Postexposure PeriodArchives of environmental health, 1960