Renal Transplantation for Wilms Tumor: Report of 20 Cases

Abstract

Renal transplantation was performed on 20 patients as treatment for Wilms tumor. In 80% the neoplasms were bilateral. Transplantation is indicated in individuals whose renal function is severely impaired or absent because of the malignancy, treatment or both. Patients who received homografts < 1 yr after treatment of the tumors had a 47% incidence of recurrence or metastases compared to a zero incidence of these problems in those whose transplants were delayed for longer periods. Survival for 2 yr or more was obtained in 75% of the recipients with unilateral neoplasms and in 38% of the patients with bilateral tumors.