Bayesian inference in multipoint gene mapping
- 1 January 1993
- journal article
- Published by Wiley in Annals of Human Genetics
- Vol. 57 (1), 65-82
- https://doi.org/10.1111/j.1469-1809.1993.tb00887.x
Abstract
The problem of ordering and mapping genes on the basis of recombinant data and radiation hybrid data is formulated as a problem of Bayesian inference for an unknown permutation. The challenging computational problems posed by this approach are shown to be resolvable using Markov chain Monte Carlo methods.Keywords
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