Three-dimensional observation of the fibroblast-like cells associated with the rat myenteric plexus, with special reference to the interstitial cells of Cajal
- 1 January 1989
- journal article
- Published by Springer Science and Business Media LLC in Cell and tissue research
- Vol. 255 (2), 343-351
- https://doi.org/10.1007/bf00224117
Abstract
An extensive cellular network becomes visible over the myenteric plexus of the rat after removal of the overlying tissues under the scanning electron microscope. The cells are mainly stellate and have many slender processes via which they interconnect. They form a three-dimensional network and are closely associated with the ganglia and nerve bundles, and also extend over the smooth muscle cells. They are considered to correspond to the interstitial cells of Cajal because of their peculiar arrangement and their topography. Transmission electron-microscopic evidence demonstrates that the majority of those cells have features of fibroblasts. Gap junctions and intermediate junctions are observed between these fibroblast-like cells, and also between them and smooth muscle cells. Examination of serial thin sections reveals that single fibroblast-like interstitial cells connect to both circular and longitudinal muscle cells via gap junctions. It is suggested that the network of interstitial cells conducts electrical signals.Keywords
This publication has 21 references indexed in Scilit:
- Close relationships between the cells of the immune system and the epithelial cells in the rat small intestineCell and tissue research, 1988
- Electrophysiology of smooth muscle of the small intestine of some mammals.The Journal of Physiology, 1986
- Electrical coupling of longitudinal and circular intestinal muscleAmerican Journal of Physiology-Gastrointestinal and Liver Physiology, 1984
- THE INTERSTITIAL-CELLS IN THE COLON OF THE RABBIT - SCANNING AND TRANSMISSION ELECTRON-MICROSCOPY1982
- Innervation of the Gastrointestinal TractInternational Review of Cytology, 1979
- Innervation of the intestinal muscular coatJournal of Neurocytology, 1972
- An electron microscopic study on the interstitial cells of the gizzard in the love-bird (Uroloncha domestica)Cell and tissue research, 1969
- The interstitial cell and its place in the concept of the autonomic ground plexusJournal of Comparative Neurology, 1966
- Electrical transmission of slow waves from longitudinal to circular intestinal muscleAmerican Journal of Physiology-Legacy Content, 1965
- THE SYMPATHETIC ENDFORMATION, ITS SYNAPTOLOGY, THE INTERSTITIAL CELLS, THE PERITERMINAL NETWORK, AND ITS BEARING ON THE NEURONE THEORY. DISCUSSION AND CRITIQUECells Tissues Organs, 1949