The two-component stomach: effects of meal particle size on fundal and antral emptying
- 1 May 1989
- journal article
- Published by Springer Science and Business Media LLC in European Journal of Nuclear Medicine and Molecular Imaging
- Vol. 15 (5), 254-259
- https://doi.org/10.1007/bf00257543
Abstract
Using a dual-headed gamma camera and a standardized egg test meal labeled with 99mTc-sulfur colloid, the quantitative emptying of the total, proximal and distal stomach in five normal subjects was characterized. The same egg meal was given to the volunteers in 3 different forms: homogenized, and as 2.5 mm and 5.0 mm cubes on 3 separate occasions for a total of 15 studies. For the total stomach emptying, the lag phase and half emptying time (T 1/2) obtained using a power exponential model were significantly shorter for the homogenized test meal than for the 2.5 mm and 5.0 mm cubed egg particles; the lag phases were 29±19 min (mean±SD) vs 55±56 (PPT 1/2′s were 71±30 min vs 91±26 (PPT 1/2s for the homogenized, 2.5 mm and 5.0 mm cubed meals were 65±26 min, 53±18 min and 64±20 min, respectively. For the distal stomach, both the peak activity (%) and time to peak activity (min) were significantly higher for the 2.5 mm cubes (43%, 54 min) and the 5.0 mm cubes (38%, 60 min) than for the homogenized eggs (16.4%, 30 min) (Pr=0.85, P<0.001 suggesting that the lag phase may correspond to the maximum filling of the distal stomach. These results demonstrate quantitatively that the proximal portion of the stomach is mainly responsible for the receipt and storage of food and the emptying of liquids, while the distal stomach appears to be primarily involved with the processing of solid food before its passage through the pylorus.Keywords
This publication has 29 references indexed in Scilit:
- Proximal, distal and total stomach emptying of a digestible solid meal in normal subjectsThe British Journal of Radiology, 1988
- Biphasic nature of gastric emptying.Gut, 1988
- Correction for tissue attenuation in radionuclide gastric emptying studies: a comparison of a lateral image method and a geometric mean methodThe British Journal of Radiology, 1984
- Gastric emptying in normal subjects--a reproducible technique using a single scintillation camera and computer system.Gut, 1983
- Distribution of a liquid meal within the stomach and gastric emptying after vagotomy and drainage operations.Gut, 1982
- Gastric emptying of varying meal weight and composition in manDigestive Diseases and Sciences, 1981
- Gastric motility and emptying in normal and post-vagotomy subjects.Gut, 1980
- Gastric, pancreatic, and biliary secretion and the rate of gastric emptying after parietal cell vagotomyThe American Journal of Surgery, 1979
- Proximal stomach and antrum in stomach emptying.Gut, 1979
- Continuous monitoring of the effect of pentagastrin on gastric emptying of solid food in man.Gut, 1976