ON THE QUESTION OF THE PRESENCE OF THYROGLOBULIN IN THE BLOOD1

Abstract

Thyroglobulin can be detected up to 1 part in 150,000 in saline or serum by the precipitin method. It can also be detected in the living animal following inj. Except Tinder certain circumstances, discussed above, no evidence for the presence of thyroglobulin could be obtained in a variety of conditions : in normal systemic blood; in blood from the normal thyroid; in either systemic or thyroid blood after an inj. of thyroxin great enough to produce a marked rise in metabolism ; in systemic blood during the metabolic rise following inj. of thyrotrophic hormone; and under any of the above conditions even after conc. of the sera or after preceding serum protein precipitation.