P-glycoprotein retains function when reconstituted into a sphingolipid- and cholesterol-rich environment
Open Access
- 1 October 2004
- journal article
- research article
- Published by Elsevier BV in Journal of Lipid Research
- Vol. 45 (10), 1910-1918
- https://doi.org/10.1194/jlr.m400220-jlr200
Abstract
No abstract availableKeywords
This publication has 47 references indexed in Scilit:
- The importance of cholesterol in maintenance of P-glycoprotein activity and its membrane perturbing influenceEuropean Biophysics Journal, 2001
- Phospholipid Flippase Activity of the Reconstituted P-Glycoprotein Multidrug TransporterBiochemistry, 2001
- Communication between Multiple Drug Binding Sites on P-glycoproteinMolecular Pharmacology, 2000
- Effects of Cholesterol and Enantiomeric Cholesterol on P-Glycoprotein Localization and Function in Low-Density Membrane DomainsBiochemistry, 2000
- Analysis of the tangled relationships between P‐glycoprotein‐mediated multidrug resistance and the lipid phase of the cell membraneEuropean Journal of Biochemistry, 2000
- P‐Glycoprotein‐Mediated Hoechst 33342 Transport Out of the Lipid BilayerEuropean Journal of Biochemistry, 1997
- MDR1 P-Glycoprotein Is a Lipid Translocase of Broad Specificity, While MDR3 P-Glycoprotein Specifically Translocates PhosphatidylcholineCell, 1996
- Mutations to Amino Acids Located in Predicted Transmembrane Segment 6 (TM6) Modulate the Activity and Substrate Specificity of Human P-glycoproteinBiochemistry, 1994
- Ultrastructural alterations in plasma membranes from drug-resistant P388 murine leukemia cellsBiochimica et Biophysica Acta (BBA) - Biomembranes, 1990
- Altered plasma membrane ultrastructure in multidrug-resistant cellsBiochimica et Biophysica Acta (BBA) - Biomembranes, 1988