Isolation and Characterization of a Mutant Mouse Lymphoma Cell Sensitive to Methyl Methanesulfonate and X Rays
- 1 April 1979
- journal article
- letter
- Published by JSTOR in Radiation Research
- Vol. 78 (1), 167-171
- https://doi.org/10.2307/3575014
Abstract
A methyl methanesulfonate-sensitive strain was isolated from L5178Y mouse lymphoma cells. This mutant, M10, is more sensitive to killing by X-rays than the parent wild-type strain. This sensitivity to the alkylating agent and ionizing radiation did not change for 11 mo. since the isolation of the mutant. The plating efficiency, doubling time and sensitivity to UV light of M10 cells are not appreciably different from those of the wild-type cells.This publication has 7 references indexed in Scilit:
- Isolation of a Mammalian Cell Mutant Sensitive to 4-nitroquinoline-1-oxideInternational Journal of Radiation Biology, 1979
- Escherichia coli gene that controls sensitivity to alkylating agentsJournal of Bacteriology, 1978
- DNA repair enzymes in ataxia telangiectasia and Bloom's syndrome fibroblastsBiochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1977
- Excision of gamma-ray induced thymine lesions by preparations from ataxia telangiectasia fibroblastsMutation Research, 1977
- Methyl methane sulfonate-sensitive mutant of Escherichia coli deficient in an endonuclease specific for apurinic sites in deoxyribonucleic acidJournal of Bacteriology, 1976
- Sensitivity to X-rays in Terms of Mitotic Delay (Sd) and Killing (Sk): Correlation betweenSdandSkfor Sub-lines of Murine Leukaemic CellsInternational Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine, 1976
- X-Ray-Induced Heritable Damage (Small-Colony Formation) in Cultured Mammalian CellsRadiation Research, 1964