Gastrointestinal function development and microbiota
Open Access
- 24 February 2013
- journal article
- review article
- Published by Springer Science and Business Media LLC in Italian Journal of Pediatrics
- Vol. 39 (1), 15
- https://doi.org/10.1186/1824-7288-39-15
Abstract
The intestinal microbiota plays an important role in the development of post-natal gastrointestinal functions of the host. Recent advances in our capability to identify microbes and their function offer exciting opportunities to evaluate the complex cross talk between microbiota, intestinal barrier, immune system and the gut-brain axis. This review summarizes these interactions in the early colonization of gastrointestinal tract with a major focus on the role of intestinal microbiota in the pathogenesis of feeding intolerance in preterm newborn. The potential benefit of early probiotic supplementation opens new perspectives in case of altered intestinal colonization at birth as preventive and therapeutic agents.Keywords
This publication has 50 references indexed in Scilit:
- Necrotizing EnterocolitisNew England Journal of Medicine, 2011
- Succession of microbial consortia in the developing infant gut microbiomeProceedings of the National Academy of Sciences, 2010
- Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newbornsProceedings of the National Academy of Sciences, 2010
- Molecular Modulation of Intestinal Epithelial Barrier: Contribution of MicrobiotaJournal of Biomedicine and Biotechnology, 2010
- Intestinal Microbial Ecology in Premature Infants Assessed with Non–Culture-Based TechniquesThe Journal of Pediatrics, 2009
- 16S rRNA gene-based analysis of fecal microbiota from preterm infants with and without necrotizing enterocolitisThe ISME Journal, 2009
- The Human Intestinal Microbiome: A New Frontier of Human BiologyDNA Research, 2009
- Microbial Prevalence, Diversity and Abundance in Amniotic Fluid During Preterm Labor: A Molecular and Culture-Based InvestigationPLOS ONE, 2008
- Development of the Human Infant Intestinal MicrobiotaPLoS Biology, 2007
- Host-Bacterial Mutualism in the Human IntestineScience, 2005