Increased Circulating Soluble Form of Fas in Patients With Dilated Cardiomyopathy

Abstract
To examine the prognostic role of the circulating soluble form of Fas (sFas), circulating sFas levels were measured in 33 patients with dilated cardiomyopathy (DCM) and 12 age-matched normal control subjects (NC) using an enzyme-linked immunosorbent assay (ELISA). Circulating sFas levels in DCM were significantly higher than those in NC (2.42±1.02 vs 1.66±0.20 ng/ml, p=0.015). Patients with DCM were stratified into 2 groups [group I (n=15): sFas ≥2.06 ng/ml; group II (n=18): sFas Jpn Circ J 1998; 62: 873 - 876)