Structure-carcinogenic activity relations in the benz[a]anthracene series. 1,7,12- and 2,7,12-trimethylbenz[a]anthracenes

Abstract

The syntheses of 1,7,12-trimethyl- and 2,7,12-trimethylbenz[a]anthracenes are described. The lack of carcinogenic activity of these compounds is discussed in relationship to the carcinogenic activity of other substituted benz[a]anthracenes.