Effect of 15(R)-15-methyl-prostaglandin E2 on iron absorption in the rat
- 1 January 1982
- journal article
- research article
- Published by Springer Nature in Cellular and Molecular Life Sciences
- Vol. 38 (1), 116-117
- https://doi.org/10.1007/bf01944561
Abstract
The administration of 15(R)-15-methyl prostaglandin E2 (15(R)-15-M-PGE2) in vivo significantly diminished the uptake of59Fe into blood, spleen, liver, femur and dried intestine of rats, whereas acetylsalicylic acid (ASA) increased the counts significantly. This effect of ASA was counteracted by 15(R)-15-M-PGE2. It is suggested that prostaglandins (PGs) might play an important role in inhibiting iron absorption at the intestinal level.This publication has 9 references indexed in Scilit:
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