Immunology Taught by Viruses
- 12 January 1996
- journal article
- review article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 271 (5246), 173-178
- https://doi.org/10.1126/science.271.5246.173
Abstract
The survival of viruses depends on the survival of susceptible hosts. The vertebrate immune system and viruses have therefore coevolved complementary facets. Evidence from various balanced virus-host relationships illustrates that immunological specificity and memory may best be defined biologically and that the mature immune system does not discriminate between “self” and “nonself.” Rather, B cells distinguish antigen patterns, whereas T cell responses depend on localization, transport, and kinetics of antigen within lymphatic organs.Keywords
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