Anemia induces accumulation of erythropoietin mRNA in the kidney and liver.
Open Access
- 1 July 1986
- journal article
- research article
- Published by Taylor & Francis in Molecular and Cellular Biology
- Vol. 6 (7), 2731-2733
- https://doi.org/10.1128/mcb.6.7.2731
Abstract
Regulation of the production of erythropoietin occurs in the kidney and liver largely through control of accumulation of erythropoietin mRNA. Erythropoietin mRNA was first detected in kidneys at 1.5 h postanemia and reached a plateau value at least 200-fold above the control value by 4 to 8 h. A 20-base sequence immediately upstream from the reported erythropoietin mRNA initiation site is complementary to a hypervariable sequence in 18S rRNA.This publication has 14 references indexed in Scilit:
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