Myelography by Means of I 131

Abstract

Iodinated human serum albumin (IHSA) ina dose of 100 to 200 microcuries I131 is delivered into the subarachnoid space by lumbar puncture. The radioactivity is recorded by means of an automatic gamma detecting scanner, using a scintillation tube (the Scintiscanner). Space occupying lesions of the spinal canal can thus be visualized. The results obtained by this technic compare favorably with the results observed by conventional oil contrast myelography. The advantages of isotope myelography over conventional myelography are: (1) A presumably non-irritating substance (IHSA) is injected, (2) IHSA does not have to be removed and, therefore, only one lumbar puncture is necessary[long dash]discomfort to the patient is markedly decreased, and (3) Since IHSA is rapidly removed from the subarachnoid space, the procedure can be repeated within 24 hrs., if necessary.