In Vitro Cultivation of the Exoerythrocytic Stage of Plasmodium Berghei in a Hepatoma Cell Line
- 1 July 1983
- journal article
- research article
- Published by American Society of Tropical Medicine and Hygiene in The American Journal of Tropical Medicine and Hygiene
- Vol. 32 (4), 682-684
- https://doi.org/10.4269/ajtmh.1983.32.682
Abstract
When inoculated with sporozoites of Plasmodium berghei, a line of hepatoma cells (HepG2-A16) derived from human liver supports the complete asexual developmental cycle of the exoerythrocytic stage. Parasites were shown to resemble parasites in vivo in hepatocytes. Subinoculation of merozoites into mice induced a red blood cell infection.This publication has 4 references indexed in Scilit:
- Entry of Plasmodium Berghei Sporozoites into Cultured Cells, and Their Transformation into TrophozoitesThe American Journal of Tropical Medicine and Hygiene, 1983
- Serological Reactivity of in Vitro Cultured Exoerythrocytic Stages of Plasmodium Berghei in Indirect Immunofluorescent or Immunoperoxidase Antibody TestsThe American Journal of Tropical Medicine and Hygiene, 1983
- Characterization of the asialoglycoprotein receptor in a continuous hepatoma line.Journal of Biological Chemistry, 1981
- In Vitro Cultivation of the Exoerythrocytic Stage of Plasmodium berghei from SporozoitesScience, 1981