Experimental observations on prophylactic and therapeutic vaccination against foot-rot in sheep

Abstract

Extract Egerton and Roberts ( 1971 Egerton, J. R. and Roberts, D. S. 1971. Vaccination against ovine foot-rot. J. comp. Path., 81: 179–185. [Crossref] [Google Scholar] ) reported that vaccines prepared from Bacteroides nodosus (Beveridge) Mraz et al. had both protective and curative effects on foot-rot induced artificially in penned sheep. Similar results were obtained in experiments on Australian properties when vaccinated sheep were exposed to natural infection (Egerton and Burrell, 1970 Egerton, T. R. and Burrell, D. H. 1970. Prophylactic and therapeutic vaccination against ovine foot-rot. Aust. vet. J., 46: 517–522. [Google Scholar] ). These findings have revived interest in the application of immunological methods to the inveterate problem of foot-rot control, an approach that had formerly been regarded as unfeasible (Beveridge, 1941 Beveridge, W. I. B. 1941. Foot-rot in sheep: a transmissible disease due to infection with Fusiformis nodosus (n.sp.). Bull. Coun. Scient. ind. Res. Melb. No. 140, [Google Scholar] ).