Multivariate birth-and-death processes as approximations to epidemic processes

Abstract

This paper presents the theory of a multivariate birth-and-death process and its representation as a branching process. The bivariate linear birth-and-death process may be used as a model for various epidemic situations involving two types of infective. Various properties of the transient process are discussed and the distribution of epidemic size is investigated. For the case of a disease spread solely by carriers when the two types of infective are carriers and clinical infectives the large population version of a model proposed by Downton (1968) is further developed and shown under appropriate circumstances to closely approximate Downton's model.