A Case of?6p- Chromosomal Aberration

Abstract

CHROMOSOMAL delections are now well documented in man. The first example was the deletion of the short arm of chromosome 18 described by De Grouchy et al.^1,2 According to the newly proposed nomenclature of the Chicago Conference³ this chromosome anomaly is refered to as "18p—". Subsequently the cri du chat or 5p— syndrome was reported by Lejeune et al⁴ and the 18q— syndrome by De Grouchy et al⁵ and Lejeune et al.⁶ Recently, Laurent et al⁷ described one case of Dq— anomaly. The present report describes a new instance of a partial deletion, namely that of the short arm of a C chromosome, probably a 6 (?6p— aberration). Report of a Case The patient, a boy, born Nov 21, 1966, was the product of the first pregnancy of a 19-year-old mother. His father was 24 years old. The child was born prematurely after 7½