Prevention of postoperative deep vein thrombosis with dipyridamole and aspirin.
- 24 April 1976
- Vol. 1 (6016), 992-994
- https://doi.org/10.1136/bmj.1.6016.992
Abstract
One hundred and sixty patients have been studied in a controlled trial of two drugs which have been in combination to prevent postoperative-deep-vein thrombosis. Both the drugs, dipyridamole (Persantin) and aspirin, were given by mouth from the evening before operation and for seven days after operation. The radioactive fibrinogen test was used to diagnose thrombosis. Of the 85 patients in the control group 24 developed thrombosis (28%). Twelve out of 85 patients (14%) in the test group were found to have thrombosis. Similar significant differences in incidence were found in the various subgroups.Keywords
This publication has 22 references indexed in Scilit:
- Effect of aspirin on postoperative venous thrombosis. Report of the Steering Committee of a trial sponsored by the Medical Research Council.1972
- LOW DOSES OF HEPARIN IN PREVENTION OF DEEP-VEIN THROMBOSISThe Lancet, 1971
- Deep vein thrombosis of the legThe American Journal of Surgery, 1970
- Factors influencing platelet function: adhesion, release, and aggregation.1970
- EFFECT OF DIPYRIDAMOLE ON THE INCIDENCE OF CLINICALLY DETECTABLE DEEP-VEIN THROMBOSISThe Lancet, 1969
- NATURAL HISTORY OF POSTOPERATIVE DEEP-VEIN THROMBOSISThe Lancet, 1969
- PLATELET ADHESIVENESS IN POSTOPERATIVE DEEP-VEIN THROMBOSISThe Lancet, 1969
- RELATIONSHIP BETWEEN POSTOPERATIVE CHANGES IN ADENOSINE-DIPHOSPHATE INDUCED PLATELET ADHESIVENESS AND VENOUS THROMBOSISThe Lancet, 1966
- EFFECT OF DIPYRIDAMOLE ON HUMAN PLATELET BEHAVIOURThe Lancet, 1965
- Venous thrombosis and pulmonary embolism. A clinico-pathological study in injured and burned patientsBritish Journal of Surgery, 1961