Mutator action by Escherichia coli strains carrying dnaE mutations
- 1 September 1977
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 74 (9), 3947-3950
- https://doi.org/10.1073/pnas.74.9.3947
Abstract
Several newly isolated temperature-sensitive dnaE mutants of E. coli exhibit powerful mutagenic action at permissive temperatures. Mutation rates for the 2 most active mutants were assayed at 4 different temperatures and compared to wild-type behavior. Temperature-resistant revertants of the original temperature-sensitive dnaE mutants exhibited lower, nearly normal, mutation rates, but no antimutator strans were found.This publication has 19 references indexed in Scilit:
- Large-scale automated isolation of Escherichia coli mutants with thermosensitive DNA replication.Proceedings of the National Academy of Sciences, 1977
- BACTERIAL MUTATOR GENES AND THE CONTROL OF SPONTANEOUS MUTATIONAnnual Review of Genetics, 1976
- Mutator gene studies in Escherichia coli: the mutT gene.1973
- Studies on the biochemical basis of spontaneous mutation. I. A comparison of the deoxyribonucleic acid polymerases of mutator, antimutator, and wild type strains of bacteriophage T4.1972
- The genetics of a mutator gene in Drosophila melanogasterMutation Research, 1970
- Genetic control of mutation rates in bacteriophageT4.1969
- Temperature-dependence of lethal and mutagenic actions of HNO2 on phage T4Biochimica et Biophysica Acta (BBA) - Specialized Section on Nucleic Acids and Related Subjects, 1964
- Transduction of lactose-utilizing ability among strains of E. coli and S. dysenteriae and the properties of the transducing phage particlesVirology, 1960
- New uses of membrane filters. I. The determination of the spontaneous mutation rate of Escherichia coli to streptomycin resistance.1955
- A Factor (or Mutator Gene) Influencing Mutation Rates in Escherichia ColiProceedings of the National Academy of Sciences, 1954