Gastric Carcinoids of Argyrophil ECL Cells
- 1 January 1980
- journal article
- research article
- Published by Taylor & Francis in Ultrastructural Pathology
- Vol. 1 (3), 411-418
- https://doi.org/10.3109/01913128009141444
Abstract
Histochemical and ultrastructural studies were carried out in four gastric carcinoids, two of which were associated with atrophic gastritis and pernicious anemia. All tumors showed intense argyrophilia and vesicular granules resembling those of endocrine enterochromaffinlike (ECL) cells in normal human gastric mucosa. Tumor cells were found to be unreactive to all the 18 available antiserums to gut hormones, including gastrin, somatostatin, glucagon, and pancreatic polypeptide. The tumors were interpreted as ECL cell argyrophil carcinoids with various degrees of differentiation and atypia.Keywords
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