Analysis of the frequency of sister chromatid exchange in different regions of chromosomes of the kangaroo rat (Dipodomys ordii)
- 1 January 1976
- journal article
- research article
- Published by Springer Nature in Chromosoma
- Vol. 56 (3), 275-287
- https://doi.org/10.1007/bf00293191
Abstract
The frequency of sister chromatid exchanges (SCEs) has been determined for C band and non-C band regions of chromosomes of the kangaroo rat after staining with the fluorescence plus giemsa (FPG) technique. After one complete round of DNA synthesis in the presence of bromodeoxyuridine (BrdU) staining of the C band regions revealed simple or complex asymmetries between chromatids. After two complete rounds of DNA synthesis in the presence of BrdU “harlequin” chromosomes were observed. Analysis of the distribution of SCE in chromosomes at their 1st and 2nd mitosis showed that relatively few exchanges occur within C band regions, although the frequency of SCEs is high at the junction between C band and non-C band chromosome regions.Keywords
This publication has 25 references indexed in Scilit:
- Evolution of Repeated DNA Sequences by Unequal CrossoverScience, 1976
- Identification withGandRBanding of the Position of Breakage Points Induced in Human Chromosomes byin VitroX-irradiationInternational Journal of Radiation Biology, 1976
- Asymmetrical C-bands and satellite DNA in manExperimental Cell Research, 1975
- Long range periodicities in mouse satellite DNAJournal of Molecular Biology, 1975
- Lateral asymmetry in the fluorescence of human Y chromosomes stained with 33 258 HoechstExperimental Cell Research, 1974
- Microfluorometric detection of asymmetry in the centromeric region of mouse chromosomesExperimental Cell Research, 1974
- Frequency and sites of sister chromatid exchanges in rat kangaroo chromosomesExperimental Cell Research, 1974
- Unequal Crossover and the Evolution of Multigene FamiliesCold Spring Harbor Symposia on Quantitative Biology, 1974
- Timing of replication of the satellite and main band DNAs in cells of the kangaroo rat (Dipodomys ordii)Experimental Cell Research, 1972
- THE FREQUENCY OF SISTER CHROMATID EXCHANGES FOLLOWING EXPOSURE TO VARYING DOSES OF H3-THYMIDINE OR X-RAYSThe Journal of cell biology, 1964