The Effect of Hormones and their Analogues Upon the Uptake of Glucose by Mouse Skin in vitro

Abstract

An experimental system is described for measuring the uptake of glucose by mouse skin in vitro. Insulin is found to stimulate and hydrocortisone to depress the glucose uptake of this system when added to the medium in concentrations comparable to those which may occur in vivo. Oestrogens, androgens and progestational agents, in contrast, have no effect at approximately physiological levels, but cause some depression of glucose uptake at high concentrations.