Chemistry of bleomycin. XXI. Metal-complex of bleomycin and its implication for the mechanism of bleomycin action.
- 1 January 1978
- journal article
- letter
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 31 (10), 1073-1077
- https://doi.org/10.7164/antibiotics.31.1073
Abstract
This review discusses the effect of the bleomycin-Ca complex and metal-free bleomycin on the binding of the antineoplastic drug to DNA.This publication has 6 references indexed in Scilit:
- A spectroscopic investigation of the metal binding site of bleomycin A2. The Cu(II) and Zn(II) derivativesBiochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1978
- Chemistry of bleomycin. XIX. Revised structures of bleomycin and phleomycin.The Journal of Antibiotics, 1978
- Bleomycin-DNA interactions: fluorescence and proton magnetic resonance studiesBiochemistry, 1977
- Intracellular reduction of the cupric ion of bleomycin copper complex and transfer of the cuprous ion to a cellular protein.The Journal of Antibiotics, 1977
- Chemistry of bleomycin. XVII. Chemical proof for the .BETA.-lactam of bleomycin.The Journal of Antibiotics, 1977
- A role for ferrous ion and oxygen in the degradation of DNA by bleomycinBiochemical and Biophysical Research Communications, 1976