Thymosin Induced Changes in the Cell Cycle of Lymphocytes from Aging Neonatally Thymectomized Rats
- 1 January 1976
- journal article
- research article
- Published by Taylor & Francis in Immunological Communications
- Vol. 5 (7-8), 695-704
- https://doi.org/10.3109/08820137609033877
Abstract
The potential role of the endocrine thymus on the cell cycle of lymphocytes from aging neonatally thymectomized rats (LAT cells) was investigated using thymosin fraction 5. Thymosin rendered LAT cells similar to normal lymphocytes with regard to reconstituting the median S+G2 phase of the LAT cell. This is the first study to demonstrate an effect of thymosin on the cell cycle of lymphocyte populations.This publication has 12 references indexed in Scilit:
- PURIFICATION AND PROPERTIES OF BOVINE THYMOSIN*Annals of the New York Academy of Sciences, 1975
- FURTHER STUDIES ON THE PROPERTIES OF LYMPHOCYTES FROM AGING NEONATALLY THYMECTOMISED RATSTransplantation, 1974
- Thymic hormones and the immune response.Physiological Reviews, 1974
- PHYTOHEMAGGLUTININ REACTIVITY OF LYMPHOID CELLS IN AGING NEONATALLY THYMECTOMIZED RATSTransplantation, 1972
- Appearance of T-cell Markers in Bone Marrow Rosette-Forming Cells after Incubation with Thymosin, a Thymic HormoneProceedings of the National Academy of Sciences, 1971
- The cell life cycle during early embryogenesis of the mouse elfriedeExperimental Cell Research, 1970
- Studies on in vitro lymphocyte proliferation in cultures synchronized by the inhibition of DNA synthesis: I. Variability of S plus G2 periods of first generation cellsExperimental Cell Research, 1969
- THYMIDINE INCORPORATION IN MIXED CULTURES OF SPLEEN CELLS FROM MICE OF DIFFERING H-2 TYPESTransplantation, 1968
- Preparation, assay, and partial purification of a thymic lymphocytopoietic factor (thymosin).Proceedings of the National Academy of Sciences, 1966